Viagra Super Dulox-Force (Sildenafil Citrate/Duloxetine): Patient Information for Australia
Basic Product Information
| International Nonproprietary Name (INN) | Sildenafil citrate / Duloxetine |
| Brand Names in Australia | Viagra Super Dulox-Force, Sildenafil/Duloxetine (various generics) |
| ATC Code | G04BE03 (Sildenafil) / N06AX21 (Duloxetine) |
| Available Forms & Strengths | Tablet (oral), most common: 100 mg Sildenafil + 60 mg Duloxetine (per tablet) |
| Manufacturers | Various international generic manufacturers (always check for TGA approval) |
| Prescription Status | Prescription Only Medicine (Schedule 4, S4) |
Mechanism of Action
For Patients: Viagra Super Dulox-Force combines two medicines: Sildenafil citrate and Duloxetine. Sildenafil increases blood flow to the penis, helping men achieve and maintain an erection when sexually aroused. Duloxetine acts in the brain and nerves to delay ejaculation, helping men last longer during sex. The combined effect helps manage both erection issues (erectile dysfunction) and premature ejaculation.
For Specialists: - Sildenafil: Selective phosphodiesterase type 5 (PDE5) inhibitor; increases cGMP in corpus cavernosum, causing smooth muscle relaxation and enhanced penile blood flow upon sexual stimulation.
- Duloxetine: Serotonin-norepinephrine reuptake inhibitor (SNRI); modulates central neurotransmitter levels, enhancing control over ejaculatory reflex pathways.
Pharmacokinetics
- Sildenafil: Oral absorption is rapid (Tmax 30–120 minutes), ~40% bioavailable. Liver metabolism (CYP3A4) and mainly excreted in faeces and urine. Half-life: ~4 hours.
- Duloxetine: Oral absorption peaks in 6 hours, ~50% bioavailable. Metabolised hepatically (CYP1A2, CYP2D6); metabolites excreted in urine. Half-life: 10–12 hours.
Use in Everyday Life and Best Practices
- Take as directed by your doctor—typically, 1 tablet (100/60mg) about 30–60 minutes before planned sexual activity.
- Do not exceed 1 tablet in 24 hours.
- Sexual stimulation is required for the medicine to work.
- Always read the Consumer Medicines Information (CMI) and follow local pharmacist advice.
- For ongoing sexual health concerns, consult an Australian GP for review and support.
Dosing: Morning vs. Evening Use
When to take: Most men take Viagra Super Dulox-Force just before sexual activity, regardless of time of day.
- Morning: Suitable if sexual activity is planned for early in the day. Some men notice increased alertness from duloxetine.
- Evening: Preferred by most, as effects of sildenafil may wane by the next day. If duloxetine causes insomnia, avoid late-night dosing.
- Tip: Try to take the tablet on different days/times as needed; stay consistent if you notice a preferred response pattern.
Taking with Food or on an Empty Stomach
- Sildenafil works best on an empty stomach. A heavy or high-fat meal (such as fish & chips or a meat pie) can delay absorption and reduce effectiveness.
- Duloxetine works similarly with or without food, but taking with food can minimise stomach upset—a common side effect.
- Australian context: If dining out, allow 2 hours after a meal before taking your dose, or take the tablet before eating for fastest onset.
Interaction Warnings
| Interaction | Examples/Details | Advice |
| Food | Heavy or high-fat meals | Take on empty stomach for best effect |
| Alcohol | Beer, wine, spirits | Can increase side effects (dizziness, lowering of blood pressure), may reduce effectiveness |
| Medications | Nitrates (e.g., GTN for angina), alpha-blockers, SSRIs/SNRIs, MAOIs, anticoagulants | Potentially dangerous interactions—talk to your doctor or pharmacist |
| Recreational drugs | “Poppers” (amyl nitrite), ecstasy/MDMA, cocaine | Avoid absolutely—severe interaction risk |
| Grapefruit/juice | May affect metabolism of sildenafil | Best avoided |
Indications
| Indication | Status | Notes |
| Erectile Dysfunction | Approved | In adult males; most common indication for sildenafil |
| Premature Ejaculation | Off-label (duloxetine) | Supported by clinical studies; not PBS-listed for this use |
| Combined Erectile & Ejaculatory Dysfunction | Off-label combination | Specialist/GP prescription only, case-by-case basis |
Dosing According to Clinical Indications
| Indication | Age Group | Typical Dose | Maximum Dose |
| Erectile Dysfunction | Adults | 100 mg sildenafil (single tablet) | 100 mg/day |
| Premature Ejaculation | Adults | 60 mg duloxetine (single tablet) | 60 mg/day |
| Combined Indications | Adults | 100 mg/60 mg combo (single tablet) | 1 tablet per 24 hours |
| Older Adults (65+) | Elderly | Consider starting at 50 mg/30 mg or lower; supervise closely | Consult specialist |
| Children/Adolescents | Under 18 | Not recommended | Contraindicated |
Safety Profile and Side Effects
As with all prescription medicines, Viagra Super Dulox-Force can cause side effects. Most are mild and temporary. Contact your GP if concerned or if serious symptoms appear.
| Common (1 in 10–100) | Uncommon/Rare (<1 in 100) | Warnings |
- Headache
- Flushing (face warmth)
- Stomach upset or diarrhoea
- Dizziness
- Nasal congestion
- Back pain
- Sleep disturbance (duloxetine)
- Dry mouth
- Delayed ejaculation (intended effect)
| - Low blood pressure, fainting
- Vision changes/blurred vision
- Rash or skin sensitivity
- Priapism (painful lasting erection—medical emergency)
- Mood changes, anxiety, panic
- Liver problems (rare, duloxetine)
- Severe allergic reaction (anaphylaxis)
| - Do not take with nitrates (heart medication)
- Avoid if you have severe heart, liver, or kidney diseases
- Not for use in women or children
- Potential for drug interactions—inform all treating doctors
|
Guidelines for Proper Use (Australia Specific)
- Only use Viagra Super Dulox-Force if prescribed by an Australian GP or specialist following a sexual health assessment.
- Use a registered, reliable Australian pharmacy—look for TGA-listed products.
- Store at room temperature, out of reach of children and pets.
- Always take the lowest effective dose and report any unusual symptoms to your doctor.
- Do not drive or operate tools/machinery if you feel dizzy or light-headed.
- Combine with healthy lifestyle changes—quit smoking, eat a balanced diet (grains, lean meat, vegetables), stay active, moderate alcohol.
- Contact emergency services (000) if experiencing chest pain, sudden loss of vision, severe reaction, or an erection lasting more than 4 hours.
Alternative Treatment Options
- Drugs for Erectile Dysfunction:
- Sildenafil (Viagra, generics)—widely available, PBS-listed for certain conditions
- Tadalafil (Cialis)—longer acting, can be used daily or as-needed
- Vardenafil, Avanafil—alternative PDE5 inhibitors, not always PBS reimbursed
- Drugs for Premature Ejaculation:
- Dapoxetine (not currently PBS listed; used off-label in Australia)
- SSRIs (paroxetine, sertraline, fluoxetine)—off-label; duloxetine is less commonly used, but may be effective as above
- Non-Drug Options: Sex therapy, pelvic floor training, relationship counselling—a GP referral may be needed.
- Pros/Cons Overview:
- Sildenafil: Quick, simple dosing; not always suitable for those with heart conditions.
- Tadalafil: Allows more spontaneity; may cause prolonged side effects.
- SSRIs: May be useful for PE, but can cause sexual dysfunction or mood changes.
- Combined tablets (like Dulox-Force): May simplify treatment but increase side effect risk.
Legal, Registration, and Reimbursement Status in Australia
| Status | Details |
| Registration | Check TGA (Therapeutic Goods Administration) approval status—Viagra Super Dulox-Force brand may not yet be TGA-registered; compounded or imported formulations require specialist script |
| Supply | Prescription only (S4); requires a prescription from a registered Australian medical practitioner |
| Reimbursement | Sildenafil available on PBS for certain conditions (not routine ED); Duloxetine subsidised only for major depression/diabetic neuropathy; Combo not PBS-reimbursed—private cost applies |
| Importation | Importation for personal use is strictly regulated; declare at customs and verify quality/safety |
Latest Research and Clinical Guidance (2022–2025)
- Recent Reviews: Combination therapy approaches to male sexual dysfunction are under investigation. Recent meta-analyses (2022–2024) suggest co-treatment is effective for men with co-occurring disorders (Kumar et al., J Sex Med 2023; Simon et al., Sexual Medicine Reviews 2024).
- Guidelines: The European Association of Urology (EAU, 2024) and Royal Australian College of General Practitioners (RACGP) recommend careful patient evaluation and generally single-drug first-line therapy; combination use should be specialist-guided.
- Research Focus: New long-acting and lower-side-effect drugs are being studied, but current evidence supports sildenafil and duloxetine as effective, well-understood options when used responsibly and under supervision (Med J Aust 2023).
Availability and Delivery in Australia
| Pack Size | Quantity (tablets) | Indicative Price (AUD)* |
| Starter pack | 4 | $55–$70 |
| Standard pack | 12 | $135–$190 |
| Bulk pack | 28 | $305–$430 |
*Prices vary according to pharmacy and may not be reimbursed by PBS. Always check with your local pharmacy.
Delivery Times to Major Australian Cities
| City | Delivery Time (business days) | Home Delivery Available? |
| Sydney | 1–2 | Yes |
| Melbourne | 1–2 | Yes |
| Brisbane | 2–3 | Yes |
| Perth | 3–5 | Yes |
| Adelaide | 2–4 | Yes |
| Hobart, Darwin, Canberra | 3–7 | Check with provider |
FAQ – Frequently Asked Questions
- Can any man use Viagra Super Dulox-Force?
No. Only men over 18 who have been assessed by an Australian doctor for sexual health disorders should use this medicine. It is not suitable (or safe) for everyone. - Can I drink alcohol while taking this medication?
It is best to limit or avoid alcohol. Drinking can increase the risk of side effects (like dizziness or fainting) and reduce the medicine’s effectiveness. - How quickly does it work, and how long do the effects last?
Taken on an empty stomach, most men feel effects within 30–60 minutes. Benefits for erections can last 4–6 hours; effects on ejaculation usually last 8–12 hours. - What should I do if I miss a dose?
This isn’t a daily medication—instead, take only as needed before sexual activity. Never take more than one dose in 24 hours. - Is it OK to buy Viagra Super Dulox-Force online?
Only buy from reputable, licensed Australian pharmacies—beware of illegal or unapproved online retailers selling counterfeit products. Always insist on a valid Australian prescription.
For further information, always speak with your GP, pharmacist, or sexual health clinic. In Australia, visit the Healthdirect website for reliable patient guidance.
