Extra Super P Force (Sildenafil / Dapoxetine) – Patient-Friendly Guide for Australia
Basic Product Information
| International Nonproprietary Name (INN) | Sildenafil citrate / Dapoxetine hydrochloride |
|---|---|
| Australian Brand Names | Extra Super P Force (not currently registered under the ARTG; considered an unregistered (“imported”) medicine for personal use under supervision of a medical professional) |
| ATC Code | G04BE03 (Sildenafil); G04BX14 (Dapoxetine) |
| Available Forms & Strengths | Tablet, oral: Sildenafil 100 mg + Dapoxetine 100 mg |
| Manufacturers | Sunrise Remedies Pvt Ltd and various Indian pharmaceutical manufacturers |
| Prescription Status (Australia) | Prescription only (Schedule 4); not TGA registered – supply under Special Access Scheme or by personal importation with prescription |
Mechanism of Action
- Sildenafil: Belongs to a class called phosphodiesterase type 5 (PDE5) inhibitors. It increases blood flow to the penis in response to sexual stimulation, helping men achieve and maintain an erection.
- Dapoxetine: Is a short-acting selective serotonin reuptake inhibitor (SSRI) that delays ejaculation by increasing serotonin activity in nerves involved in ejaculation control.
For Professionals: Sildenafil blocks PDE5 enzyme, increasing cyclic GMP (cGMP) in penile tissue; this smooth muscle relaxation and arterial dilatation produce an erection if sexual stimulation is present. Dapoxetine inhibits presynaptic serotonin reuptake in CNS neurons, prolonging the time to ejaculation via somatic and autonomic pathways.
Pharmacokinetics
- Absorption: Both sildenafil and dapoxetine are rapidly absorbed after oral intake; peak blood levels occur at approximately 1–2 hours (sildenafil) and roughly 1–2 hours (dapoxetine).
- Metabolism: Metabolised in the liver mainly by CYP3A4 (both drugs), with minor pathways including CYP2D6 and CYP2C9 (dapoxetine).
- Elimination: Sildenafil excreted mainly as metabolites in faeces and urine; dapoxetine mainly in urine as glucuronide/sulphate conjugates.
- Duration of Action: Sildenafil: 4–6 hours. Dapoxetine: modest efficacy for up to 6 hours post-dose.
Use in Everyday Life & Best Practices
Typical Uses & Doses:
Extra Super P Force is intended for adult men diagnosed with both erectile dysfunction (ED) and premature ejaculation (PE). Typically, one tablet (Sildenafil 100mg + Dapoxetine 100mg) is taken when needed, about 1–3 hours before anticipated sexual activity. The dose must not exceed one tablet within 24 hours.
- Do not use more than once daily.
- Swallow the tablet whole with a full glass of water.
- Must only be used if prescribed and under supervision of an Australian healthcare provider.
- Do not cut or split the tablet, as dose uniformity cannot be assured.
Please note, sexual arousal is still needed for Extra Super P Force to work. The combination is not recommended for men who do not have both conditions (ED, PE).
Dosing: Morning vs Evening
- Morning dosing: May not always be practical, as the effect window is short. Not for routine use outside planned sexual activity.
- Evening dosing: More popular; suits evening intimacy. Avoid following a heavy meal (see below) and alcohol.
- Tips for Regularity: Take only when sexual activity is planned. Do not use as a daily routine tablet.
Taking With Food vs On an Empty Stomach
- High-fat meals (e.g., full English breakfast, fish & chips) may delay the onset of sildenafil, but not dapoxetine.
- For best results, take on an empty stomach or after a light, low-fat meal.
- Avoid large or greasy meals within 2 hours of taking the tablet.
- No need to avoid typical Australian balanced meals; simply moderate timing around heavy/evening meals.
Interaction Warnings
| Interaction | Advice |
|---|---|
| Alcohol | Raises risk of side effects (dizziness, fainting); avoid or strictly limit alcohol on days you use this medicine. |
| Grapefruit juice | Slows drug breakdown in liver; avoid grapefruit and grapefruit juice. |
| Nitrates (chest pain meds) | NO sildenafil/dapoxetine – dangerous drop in blood pressure may result. Includes GTN spray, isosorbide mononitrate, etc. |
| Other ED medications | Do not combine with other ED treatments (e.g., tadalafil, vardenafil). |
| SSRIs, MAOIs, Lithium | Consult your healthcare provider. Risk of serotonin syndrome with certain antidepressants. |
| Alpha-blockers (e.g., tamsulosin) | May exacerbate blood pressure drops. Monitor closely. |
| Other medications | Always inform your doctor or pharmacist about all medicines and supplements you use. |
Indications
| Indication | Status |
|---|---|
| Erectile dysfunction (ED) with premature ejaculation (PE) in adult men | Off-label/Non-TGA registered combination (components individually approved) |
| Erectile dysfunction (ED) alone | Use single-ingredient ED medicines |
| Premature ejaculation (PE) alone | Use single-ingredient dapoxetine or behavioural therapy |
Dosing According to Clinical Indications
| Population | ED + PE (Usual Dose) | Comments / Adjustments |
|---|---|---|
| Adult men (18–64 years) | 1 tablet (Sildenafil 100 mg / Dapoxetine 100 mg) as needed, 1–3 hours pre-sex | Max: 1 tablet/24h. Start with a lower dose of single components if needed. |
| Elderly (65+ years) | Cautious use. Consider starting with half-tablet or lower strengths; consult doctor. | Higher sensitivity to side effects. |
| Children / Adolescents | Not indicated; do not use. | Not recommended or studied. |
Safety Profile & Side Effects
| Frequency | Possible Side Effects |
|---|---|
| Very common (>1 in 10) | Headache, nausea, facial flushing |
| Common (1 in 10 to 1 in 100) | Dizziness, diarrhoea, nasal congestion, dryness of mouth, back pain, vision changes (blue/blurred vision), insomnia, anxiety |
| Uncommon (1 in 100 to 1 in 1,000) | Fast heart rate, PR prolongation, palpitations, low blood pressure, mild nosebleed |
| Rare (<1 in 1,000) | Priapism (prolonged/painful erection – seek urgent help), fainting, serotonin syndrome (mainly with other medicines), allergic reactions |
- Not recommended for men with severe heart or liver disease, certain eye disorders, or major depression.
- See your doctor if you get chest pain, loss of vision, or hearing changes after use.
Guidelines for Proper Use – Australia Context
- Always use under the supervision of your Australian GP or urologist.
- Store below 25°C away from moisture and sunlight (typical Australian ambient conditions).
- Do not drive or operate machinery if you feel dizzy or lightheaded after taking.
- Follow your doctor’s advice about heart or blood pressure checks before starting treatment.
- Tell your pharmacist about all medications, herbal, and non-prescription products you use.
- If you miss a planned dose, do not double up—use only as required before sexual activity.
Alternative Treatment Options
- Sildenafil (as Viagra, Silvasta, Sandoz Sildenafil, etc.): Widely available and reimbursed by the PBS when prescribed for specific approved indications.
- Dapoxetine (as Priligy): Available under private prescription. Not PBS reimbursed.
- Tadalafil, Vardenafil: Other PDE5 inhibitors, single-ingredient therapy; option for men with ED but not PE.
- Behavioural therapies/couples therapy, pelvic floor exercises for PE: Non-medicinal, effective for some men.
- Topical desensitisers (lidocaine spray/cream): Non-systemic option for PE.
Pros & Cons: Combination tablets may improve adherence for men with both conditions; however, single-ingredient options are TGA-approved, more familiar to clinicians, and are reimbursed in some indications.
Legal, Registration & Reimbursement Status in Australia
- Currently, Extra Super P Force is not included in the Australian Register of Therapeutic Goods (ARTG); not PBS listed.
- May be legally brought into Australia by individual patients under the Personal Importation Scheme (with TGA prescription from a licensed doctor).
- Suppliers must comply with TGA and AQIS import rules; product must be for personal use and not re-sale.
- Safety, efficacy and quality assessment remains the responsibility of the prescribing doctor.
Latest Research & Clinical Guidance (2022–2025)
- Combination therapies for ED and PE are under investigation, with growing evidence for their effectiveness (see: Belkin et al., 2023, BJU International; Hackett G, 2023, Sexual Medicine Reviews).
- Australian and international guidelines (see: EAU 2022, AUA 2023, Andrology Australia) continue to recommend single-ingredient therapy as first-line, reserving combinations for men with proven co-morbidity.
- Safety on long-term regular use is not yet robustly established for the fixed-dose combination.
Availability & Delivery
| Pack Sizes | Average Price (AUD) | Estimated Delivery Times (business days) |
|---|---|---|
| 4 tablets | $35–$50 | Sydney: 2–3; Melbourne: 2–3; Brisbane: 3–5; Perth: 5–7; Adelaide: 2–4; Darwin, Hobart: 5–8 |
| 8 tablets | $60–$85 | Sydney: 2–3; Melbourne: 2–3; Brisbane: 3–5; Perth: 5–7; Adelaide: 2–4; Darwin, Hobart: 5–8 |
| 12 tablets | $80–$110 | Sydney: 2–3; Melbourne: 2–3; Brisbane: 3–5; Perth: 5–7; Adelaide: 2–4; Darwin, Hobart: 5–8 |
Delivery via registered pharmacy mail or courier; ensure compliance with TGA import regulations.
Frequently Asked Questions
1. Do I need a prescription for Extra Super P Force in Australia?Yes. You must have a valid prescription from a registered Australian doctor, and the product must be imported legally for personal use.
2. Is Extra Super P Force safe if I have other health conditions?
If you have a history of heart, liver, or neurological conditions or are taking certain medications (see above), consult your GP to assess suitability and safety.
3. Can I drink alcohol with this medicine?
Avoid or strictly limit alcohol, as it can worsen side effects such as dizziness and fainting. Alcohol may also reduce the effectiveness of the medication.
4. Will my Medicare or private health insurance pay for Extra Super P Force?
No. This combination is not covered by the PBS or most private insurance; costs are usually out-of-pocket.
5. What should I do if I experience persistent erection or other severe effects?
Seek urgent medical help if your erection lasts more than 4 hours (priapism) or you experience chest pain, loss of vision, or signs of an allergic reaction.
